Transgenic Mouse: Methods and Portocols

Title: Transgenic Mouse: Methods and Portocols

Description:

392 pages

Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of

readily reproducible

methods for working with mice, and particularly for generating mouse models that will

enable us to better

understand gene function. Described in step-by-step detail by highly experienced

investigators, these proven techniques include new methods for conditional, induced

knockout, and transgenic mice, as well as for working with mice in such important

research areas as immunology, cancer, and atherosclerosis. Such alternative

strategies as random mutagenesis and viral gene transduction for studying gene

function in the mouse are also presented.

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