Zhou Songyang, "Telomeres and Telomerase: Methods and Protocols" (2nd
Zhou Songyang, "Telomeres and Telomerase: Methods and Protocols" (2nd edition)
Publisher: Humana Press | ISBN: 1617790915 | edition 2011 | PDF | 191 pages | 5.3 mb
New and rapid advances in technology have equipped us with a variety of tools and platforms to ask fundamental questions of telomere regulation and have allowed investigators to carry out experiments using diverse model systems.For example, proteomic, genomic, and molecular approaches have afforded us unprecedented insight into the complex protein interaction networks at work on the telomere chromatin and the detailed information regarding telomere dynamics in response to stress or stimuli.Telomeres and Telomerase: Methods and Protocols, Second Edition builds upon the telomerase assays featured in the popular first edition to encompass many different assays that allow investigators to query the function of telomere proteins and the responses of the telomere DNA, including detailed examinations of biochemical, molecular, and proteomic approaches.Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls.
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Molecular Biology Series Telomeres And Telomerase Methods In Molecular Biology Protein Interaction Interaction Networks Laboratory Protocols Humana Press Unprecedented Insight Molecular Approaches Necessary Materials Rapid Advances Model Systems Chromatin
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